HomeProjectsBiomedical Sciences and Healthcare TechnologiesNon-invasive Diagnosis of Liver Fibrosis

Non-invasive Diagnosis of Liver Fibrosis

Project Quick Facts

Principal Investigator

  • Prof. CHEN Weitian

    Department of Imaging and Interventional Radiology

  • Funding

    Innovation and Technology Commission

    Hong Kong Science and Technology Park

  • Patent

    3 USA patents granted, 1 USA patent and 3 China patent applications pending

This project provides advanced medical solutions for non-invasive diagnosis of liver fibrosis based on MRI and AI technologies. The current gold standard for diagnosis of liver fibrosis is liver biopsy, which is invasive and impractical for screening and treatment monitoring. The existing non-invasive diagnostic techniques still have significant limitations. The project aims to develop a product to fill the gap of diagnosis of liver fibrosis. Our solutions are convenient and easy to operate. The robustness and effectiveness of our technology have been demonstrated in pilot clinical studies. The diagnostic value of our technology has been demonstrated in pilot clinical studies. 

Relative collagen content of the liver of 8 patients measured using our technology: No liver fibrosis (a-d); Early-stage liver fibrosis (e-h)

Uniqueness and Competitive Advantages:

  • Quantifies liver fibrosis directly rather than indirect stiffness measurement. This reduces the influences from confounding factors and improves the accuracy of detecting early-stage fibrosis.
  • Does not require extra hardware and has a convenient workflow. This reduces the cost.

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